A Camel to the Rescue: Nanobodies against SARS-CoV-2

Created with BioRender.com Amid the COVID-19 pandemic, antibodies have been under the spotlight as potential therapeutics. Antibodies patrol the body and bind to their specific target region, known as an epitope, on an antigen. In humans, antibodies consist of 2 heavy chains and 2 light chains held together by disulfide bonds (see graphical abstract). However, asContinue reading “A Camel to the Rescue: Nanobodies against SARS-CoV-2”

Toxoplasma gondii – a new cancer fighting superhero

“Life will win over death, and light will win over darkness”– Volodymyr Zelenskyy, President of Ukraine “I would not be here today if it wasn’t for you and your discovery” – said Tomas Dahl during the meeting in Stockholm. Tomas was one of the cancer patients who had the prestigious chance to share their storyContinue reading “Toxoplasma gondii – a new cancer fighting superhero”

A step towards affordable cell therapy using mRNA technology

This image was created with Biorender.com A decade ago, a novel immunotherapy ravaged two pounds of cancer cells and revolutionized the treatment of blood cancer. This immunotherapy isolated T cells from a patient and inserts a gene encoding synthetic chimeric antigen receptor (CAR) ex-vivo into T cells. These CARs contain regions to redirect T cellsContinue reading “A step towards affordable cell therapy using mRNA technology”

A Combo offer to deal with Melanoma: Latest Development with Immune Checkpoint Inhibitors

Modern Science has experienced huge breakthroughs over the last decades, one of the major ones being the discovery of immune checkpoints and their inhibitors. The checkpoint inhibitors revolutionized the stagnant field of cancer biology and were responsible for the rise of cancer immunotherapies. Immunotherapies command the immune system to destroy tumors by using antibodies againstContinue reading “A Combo offer to deal with Melanoma: Latest Development with Immune Checkpoint Inhibitors”

Immunology: Bigger than it seems

A World Immunology Day 2021 special post Immunology is the study of immune cells that are the body’s defense against everything that is foreign and can damage our body. Immune systems have been around for millions of years, protecting all sorts of organisms including plants and bacteria from harm. The field of Immunology has seenContinue reading “Immunology: Bigger than it seems”

Memory T cells persist after neoantigen vaccine in melanoma patients

Vaccines are not oblivious, especially in 2021, but when we say ‘vaccine’ we usually refer to something that can prevent an infection. Have you ever heard of therapeutic vaccines? One revolutionary therapeutic vaccine for melanoma, a new personal neoantigen vaccine called NeoVax, was developed by Ott et al. and its early clinical outcome was publishedContinue reading “Memory T cells persist after neoantigen vaccine in melanoma patients”