Tag: immune checkpoint
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Buddisode 36 – IL-17A and ICI-induced autoimmune thyroiditis
In this Buddisode, we sit down with Dr. Melissa Lechner from the Division of Endocrinology, Diabetes, and Metabolism at the UCLA David Geffen School of Medicine to discuss her recent paper about the mechanisms behind immune checkpoint inhibitor-induced autoimmune thyroiditis. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science…
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Sugar, yes please, won’t you come and put it down on macrophage: A song of sugars and cancers
Our immune system is a well-orchestrated fort, equipped to fight all kinds of nasty that attack our body. Unfortunately, some attackers come well prepared with weapons for immune evasion and can escape or even confuse our immune system, such as with cancer. In the recent years, we have seen a rise of new potential therapies…
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Unleashing the Anti-tumor Immune Cells with Dostarlimab
Blocking checkpoint proteins enhance immune cell activity In healthy individuals, the immune system is intricately regulated to maintain homeostasis. Consider it as a see-saw: on the one hand, excessive immune activation in the absence of harmful pathogens may manifest as autoimmune diseases; on the other hand, inadequate immune defense creates vulnerability during infections. The immune…
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