The Battle of the Ts: Regulatory CD8+ T cells suppress autoimmunity associated CD4+ T cells

“The enemy of my enemy is my friend” – Proverb Over years of evolution, our immune system successfully dealt with a variety of foreign invaders such as viruses, bacteria, fungi, and uni- and multi-cellular parasites. Starting 1900s, doctors and scientists started discovering a faulty immune system (mainly T and B cells) in patients, attacking theirContinue reading “The Battle of the Ts: Regulatory CD8+ T cells suppress autoimmunity associated CD4+ T cells”

A Camel to the Rescue: Nanobodies against SARS-CoV-2

Created with Amid the COVID-19 pandemic, antibodies have been under the spotlight as potential therapeutics. Antibodies patrol the body and bind to their specific target region, known as an epitope, on an antigen. In humans, antibodies consist of 2 heavy chains and 2 light chains held together by disulfide bonds (see graphical abstract). However, asContinue reading “A Camel to the Rescue: Nanobodies against SARS-CoV-2”

OMV-based vaccines for SARS-CoV-2

Picture source: Dr. Matt Delisa, Locally Sourced Science The development, production, and manufacturing of large-scale vaccines are necessary for control of the pandemic internationally- to divide the load as well as keep vaccines up to date with the emerging variants- especially in underdeveloped countries. The vaccination has turned into a race between SARS-CoV-2 and scientists,Continue reading OMV-based vaccines for SARS-CoV-2

Now take a deep breath and calm your immune system.

Throughout the COVID-19 outbreak we witnessed the good (rapid vaccine development and production, alongside the amazing work done by our healthcare workers), the bad (misinformation spreading) and the ugly (higher mortality rates due to COVID-19 infection and post-infection COVID-19 syndrome). While, during the peak of crisis researchers prioritized the treatments and side effects, now weContinue reading “Now take a deep breath and calm your immune system.”

SARS-CoV2 Mu variant is resistant towards serum antibody neutralization

Picture source: 11Alive It is no news, vaccination against SARS-CoV-2 enormously decreases chances of severe side effects and hospitalizations, but vaccinated individuals are still not spared in this pandemic. This is mainly because of the rare breakthrough cases being reported by vaccinated people mostly caused by the newer SARS-CoV-2 strains. As of September 2021, thereContinue reading “SARS-CoV2 Mu variant is resistant towards serum antibody neutralization”

The COVID-19 Research Rundown

The grim COVID-19 pandemic shows no sign of stopping, with the Delta variant bringing new waves of infections across the world. Thankfully, the vaccination efforts are running on full throttle leading to rarer cases of adverse effects, at least amongst the vaccinated crowds (1). And now that the Pfizer mRNA vaccine has been approved byContinue reading “The COVID-19 Research Rundown”

SARS-COV-2 Delta Variant: The Uninvited Guest and How to Deal with it.

Picture source: WHO SARS-CoV-2 is an RNA virus- ergo it was expected to mutate. Unfortunately, about 163 million Americans had already gotten the shot before the new Delta (B.1.617.2) variant emerged. This new variant, first identified in India, was seen to be much more contagious than the previous versions. The spreading of misinformation in publicContinue reading “SARS-COV-2 Delta Variant: The Uninvited Guest and How to Deal with it.”

Plants- The New COVID19 Vaccine Manufacturers

Remember how we were taught in school that plants provide us with food, oxygen, rain, and shelter? Well, get ready to teach the new generation about the newest addition to that list! While we witnessed the emergence of new and rapid vaccine production during the COVID-19 pandemic using viral vectors (Sputnjik, AstraZeneca) and mRNA vaccinesContinue reading “Plants- The New COVID19 Vaccine Manufacturers”

Fighting a Long Fight: Long Term Effects of COVID-19

The term ‘long covid‘ did not originate from a doctor, well, not from a medical doctor at least. Dr. Elisa Perego, an archaeologist at the University College London, used the term on her Twitter account to describe her experience of a post-COVID-19 disease1. Although the term long covid came from “patients“, National Institute for HealthContinue reading “Fighting a Long Fight: Long Term Effects of COVID-19”

Are COVID vaccines still safe? Blood clots, the mystery behind them, and the solution.

The light at the end of this dark tunnel (the year 2020) is finally visible, as large scale vaccinations are in progress. Whether one stayed at home or worked endlessly to bring this pandemic to an end, our team work has contributed to end the terror. Unfortunately, a new hurdle arose in the battle againstContinue reading “Are COVID vaccines still safe? Blood clots, the mystery behind them, and the solution.”