Tag: CD4

  • Shifting Paradigms: T Cells, FlipFlops, and Reversed T Cells

    Shifting Paradigms: T Cells, FlipFlops, and Reversed T Cells

    You must have come across the fundamental concepts of T cell development during your immunology class. Briefly, in the thymus, T cells expressing both CD4 and CD8 coreceptors interact with MHC molecules on thymic epithelial cells to make lineage fate decisions. CD4+ cells interact with MHCII and are called T helper cells while CD8+ cells […]