Tag: cancer
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Bridging the “gap” between CAR and solid tumors
Picture credit: flickr.com Since first approved by the FDA in 2017, T cells with chimeric antigen receptors (CAR T) have revolutionized the treatment of blood cancers like leukemia and lymphoma. Since then, research has been focused on improving the CARs to treat a wide range of cancers including solid tumors – that have proved to…
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Your T cells can outlive you!
Did you ever question mortality? Some people believe in the existence of living elements (like our soul), even after our death. For us biologists, there is a standard consideration of cells being mortal. In human biology, there is even a limitation of 50 – 60 divisions that cells can undergo, known as a ‘Hayflick limit’.…
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Monolog 7 – Cancer is an immune disease
In this monolog, Natalie explains how cancer is a disease of the immune system. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw Send us your queries/questions/suggestions at antibuddies1@gmail.com.
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Monolog 6 – TIM3 and breast cancer
In this breast cancer awareness month special monolog, Tanu talks about the challenges faced for breast cancer research and finding an effective treatment that works for everyone. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal club at our…
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Buddisode 17 – IgM: the key to early neoantigen recognition
In this buddisode, Eugenio, Natalie, and Jatin sit down with Dr. Claudia Jakubzick from Dartmouth University. They discus Claudia’s 2018 publication that elucidated the role of natural IgM in the recognition of neoantigens in absence of PAMPs. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science Communication & Immunology…
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Buddisode 15 – Mitochondria is the powerhouse of TILs
In this buddisode, we sit down with Dr. Yi-ru Yu, a post doctoral researcher at the department of oncology (University of Lausanne, Switzerland) to talk about his recent article studying mitochondrial dynamics in the exhaustion of tumor infiltrating lymphocytes (TILs). Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication &…
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Monolog 1 – No mercy for cancer
In this monolog, Jatin briefly discusses the recent study from Lai et al. about FLT3L-secreting CAR T cells that successfully elicited a polyclonal immune response in Her2 and OVA co-expressing tumor models. Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Join us on our monthly journal…
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Buddisode 9 – Cancer nano-immunotherapy #2
In this Buddisode, Antia and Jatin continue to discuss about the recent developments in cancer nano medicine. Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Send us your queries/questions/suggestions at antibuddies1@gmail.com. Sources: https://www.nature.com/articles/s41577-019-0269-6
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Buddisode 8 – Cancer nano-immunotherapy #1
In this Buddisode, Antia and Jatin discuss about the recent developments in cancer nano medicine. Part 2 will be out soon. Check out our memes on Facebook (@antibuddies) and Twitter (@antibuddiesP). Website: Antibuddies – Science Communication & Immunology (Antibuddies.org) Send us your queries/questions/suggestions at antibuddies1@gmail.com. Check out Public journal club here https://www.facebook.com/Publicjournalclub/ Sources: https://www.nature.com/articles/s41577-019-0269-6
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Sugar, yes please, won’t you come and put it down on macrophage: A song of sugars and cancers
Our immune system is a well-orchestrated fort, equipped to fight all kinds of nasty that attack our body. Unfortunately, some attackers come well prepared with weapons for immune evasion and can escape or even confuse our immune system, such as with cancer. In the recent years, we have seen a rise of new potential therapies…
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