Tag: autoimmunity

  • Buddisode 36 – IL-17A and ICI-induced autoimmune thyroiditis

    In this Buddisode, we sit down with Dr. Melissa Lechner from the Division of Endocrinology, Diabetes, and Metabolism at the UCLA David Geffen School of Medicine to discuss her recent paper about the mechanisms behind immune checkpoint inhibitor-induced autoimmune thyroiditis. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – Science […]

  • Buddisode 24 – Type I vs Type II interferons in autoimmunity

    In this Buddisode, Dara & Jatin sit down with Adam Fike from Ziaur Rahman’s lab at Penn State University. The discussion entails their 2020 publication that teased apart the contribution of Type I and Type II interferons in TLR7-mediated systemic autoimmunity. Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast). Website: Antibuddies – […]

  • The Battle of the Ts: Regulatory CD8+ T cells suppress autoimmunity associated CD4+ T cells

    The Battle of the Ts: Regulatory CD8+ T cells suppress autoimmunity associated CD4+ T cells

    “The enemy of my enemy is my friend” – Proverb Over years of evolution, our immune system successfully dealt with a variety of foreign invaders such as viruses, bacteria, fungi, and uni- and multi-cellular parasites. Starting 1900s, doctors and scientists started discovering a faulty immune system (mainly T and B cells) in patients, attacking their […]

  • An Unexpected Linkage: The Gut-Skin Axis

    An Unexpected Linkage: The Gut-Skin Axis

    Created with BioRender.com In the public discussion of microbes, there is often a negative connotation attached to microbes such as bacteria, viruses, fungi, and parasites due to the presence of pathogenic individuals in each category. However, microbes are not synonymous with pathogens. For instance, some gut bacteria are well-acknowledged for their importance in the nutrient […]

  • New Role for Ductal Cells in Type 1 Diabetes

    New Role for Ductal Cells in Type 1 Diabetes

    Despite owning the same genetic material, our cells carry out highly specialized functions and vary from each other in many phenotypic aspects. Interestingly, when in troubled times (i.e., under stressful conditions) certain cells change their characteristic protein expression and turn into something completely unexpected, to help us survive. Fasolino and group shed light on such […]