Journal Club

Join us for the livestream on Facebook or watch recorded sessions on the YouTube channel.

Learn more the importance of Adenosine to Inosine editing in preventing spontaneous Type I IFN responses Article: https://www.cell.com/immunity/fulltext/S1074-7613(21)00343-5
Learn more on the suppressive effects of obese tumor microenvironment in T cell function.
Article: https://rupress.org/jem/article/219/3/e20210042/212992/Suppressive-effects-of-the-obese-tumor?searchresult=1
Learn more about STAT2 deletion on dendritic cells impairs cytotoxic T cell functions
Article of Discussion: https://www.tandfonline.com/doi/full/10.1080/2162402X.2020.1860477
Learn about how neutrophils change as a function of age and sex.
Article of Discussion: https://www.nature.com/articles/s43587-021-00086-8
Learn about the role of pancreas sympathetic signaling in type 1 diabetes.
Article of Discussion: https://www.science.org/doi/10.1126/sciadv.abb2878.gov/33223341/
Learn about Guillain-Barré syndrome and a SIGLEC10 variant associated with the disease.
Article of Discussion: https://pubmed.ncbi.nlm.nih.gov/33223341/
Learn about follicular CD8+ T cells in Systemic autoimmune disease.
Article of Discussion: https://www.sciencedirect.com/science/article/abs/pii/S0896841121000986?dgcid=author
Learn about STAT3 mutations that promote defects in CD8+ T cell tolerance in Type 1 Diabetes patients.
Article of Discussion: https://www.jimmunol.org/content/earl…
Learn about glycosylation and tumor immunology in this journal club with Dr. Sandra van Vliet from the Amsterdam Medical Center.
Article of Discussion: https://www.frontiersin.org/articles/10.3389/fonc.2020.01622/full?report=reader
Learn about the role of TRAF3 as it restrains the regulators of TCR signaling to promote T cell activation. Tina shares her work about the involvement of brk, dok1, and TRAF3 proteins in regulating TCR signals.
Article of Discussion: https://www.jimmunol.org/content/early/2021/06/18/jimmunol.2001220
In this discussion, Dr. Debbie Yablonski from the Israel Institute of Technology talks to us about her lab’s recent publication where they dissect the role of Itk in integrating signals from the TCR and CD28.
Article of discussion: https://www.jimmunol.org/content/early/2021/04/30/jimmunol.2001053
In this discussion, Dr. Danyivid Olivares-Villagomez from Vanderbilt University medical school talks to us about his lab’s recent publication regarding the role of osteopontin in intestinal immunity and homeostasis.
Article of discussion: Osteopontin and iCD8α cells promote intestinal intraepithelial lymphocyte homeostasis (nih.gov)
Join us for a session with Dr. Ian Myles from the NIH where he talks about the CD8-dependent immunity conferred by breast milk.
Article of Discussion: Frontline Science: Breast milk confers passive cellular immunity via CD8-dependent mechanisms – PubMed (nih.gov)
Dr. Bingfei Yu Talks about her research on the XIST complex that maintains X-inactivation in B cells and its implications in COVID19 and Autoimmunity.
Article of Discussion: B cell-specific XIST complex enforces X-inactivation and restrains atypical B cells: Cell
In today’s discussion, Dr. Martin Stacey from the University of Leeds talks about his recent publication where they report that the cytokine IL-36y senses pathogenic molecules.
Article of discussion: https://pubmed.ncbi.nlm.nih.gov/33326792/
In today’s discussion, Dr. Nina Le Bert from Duke-NUS medical school talk about her recent publication where they report some stark differences in the immune response found in asymptomatic vs symptomatic patients.
Article of discussion: https://rupress.org/jem/article/218/5/e20202617/211835/Highly-functional-virus-specific-cellular-immune
In today’s discussion, Eddie Cano-Gamez from the Wellcome Sanger institute tells us about his recent publication where they found a gradient of effectorness in CD4+ T cells in response to cytokines.
Article of discussion: https://pubmed.ncbi.nlm.nih.gov/32286271/
In today’s discussion, Drs. Bosio & Schwarz talk about the serum lipid profiles in moderate and severe COVID19 patients.
Article of discussion: https://www.medrxiv.org/content/10.1101/2020.07.09.20149849v2
Learn about the safety and efficacy data of the COVID19 vaccines with us!
In today’s discussion, Dr. Sharma will talk about a new technique to identify TCR epitopes from large peptide-coding libraries.
Article of discussion: https://www.nature.com/articles/s41467-019-12444-7
In today’s discussion, Dr. Walsh emphasizes the benefits of combining oncolytic virus therapy with adoptive T cell therapy against tumors.
Article of discussion: https://www.jci.org/articles/view/126199
In today’s discussion, Dr, Wack tells us about Influenza and its effect on anti-bacteria immunity
Article of discussion: https://www.nature.com/articles/s41590-019-0568-x
In today’s discussion, Dr. JM Inclan will educate the audience about a novel inhibitory role of basophils in Helminthic infections.
Article of discussion: https://www.nature.com/articles/s41590-020-0753-y
In today’s discussion, Maria tells us about circadian rhythms in Tregs that affect inflammation.
Article of discussion: https://www.nature.com/articles/s41467-020-15525-0
In today’s discussion, Samriti tells us about prediction of clinical efficacy in anti-PD1 blockade therapy with PD1 expression on Tconv and Treg cells.
Article of discussion: https://www.nature.com/articles/s41590-020-0769-3

In today’s discussion, Tanu tells us about the role of maternal antibodies in protection from enteric pathogens in neonates.
Article of discussion: https://www.nature.com/articles/s41586-019-1898-4
In this discussion, Maria tells us about the importance of Galectin-1 in resolving sjogren’s syndrome-like disorder in mice.
Article of discussion: https://www.pnas.org/content/117/12/6630
In this episode, we discuss the effect of SARS CoV2 on dendritic cells and T cell responses through the article from Allo et al. Article of discussion: https://www.pnas.org/content/117/12/6630
How is Bcl6 important in SLE? Find out here!
Article of discussion: https://www.nature.com/articles/s41423-019-0268-3
How does the oncolytic virus delta-24 RGD performs against certain glioma mouse models? Find out here!
Article of discussion: https://www.nature.com/articles/s41467-019-10043-0
What is the role of CD28 for activation of T cells? When is it dispensable? Is it required for anti-tumor immunity? Find out here!
Article of discussion: https://pubmed.ncbi.nlm.nih.gov/28919076/
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