Learn about STAT3 mutations that promote defects in CD8+ T cell tolerance in Type 1 Diabetes patients. Article of Discussion: https://www.jimmunol.org/content/earl…
Learn about the role of TRAF3 as it restrains the regulators of TCR signaling to promote T cell activation. Tina shares her work about the involvement of brk, dok1, and TRAF3 proteins in regulating TCR signals. Article of Discussion: https://www.jimmunol.org/content/early/2021/06/18/jimmunol.2001220
In this discussion, Dr. Debbie Yablonski from the Israel Institute of Technology talks to us about her lab’s recent publication where they dissect the role of Itk in integrating signals from the TCR and CD28. Article of discussion: https://www.jimmunol.org/content/early/2021/04/30/jimmunol.2001053
In today’s discussion, Dr. Martin Stacey from the University of Leeds talks about his recent publication where they report that the cytokine IL-36y senses pathogenic molecules. Article of discussion: https://pubmed.ncbi.nlm.nih.gov/33326792/
In today’s discussion, Eddie Cano-Gamez from the Wellcome Sanger institute tells us about his recent publication where they found a gradient of effectorness in CD4+ T cells in response to cytokines. Article of discussion: https://pubmed.ncbi.nlm.nih.gov/32286271/
Learn about the safety and efficacy data of the COVID19 vaccines with us!
In today’s discussion, Dr. Sharma will talk about a new technique to identify TCR epitopes from large peptide-coding libraries. Article of discussion: https://www.nature.com/articles/s41467-019-12444-7
In today’s discussion, Dr. Walsh emphasizes the benefits of combining oncolytic virus therapy with adoptive T cell therapy against tumors. Article of discussion: https://www.jci.org/articles/view/126199
In today’s discussion, Dr. JM Inclan will educate the audience about a novel inhibitory role of basophils in Helminthic infections. Article of discussion: https://www.nature.com/articles/s41590-020-0753-y
In today’s discussion, Samriti tells us about prediction of clinical efficacy in anti-PD1 blockade therapy with PD1 expression on Tconv and Treg cells. Article of discussion: https://www.nature.com/articles/s41590-020-0769-3
In today’s discussion, Tanu tells us about the role of maternal antibodies in protection from enteric pathogens in neonates. Article of discussion: https://www.nature.com/articles/s41586-019-1898-4
In this discussion, Maria tells us about the importance of Galectin-1 in resolving sjogren’s syndrome-like disorder in mice. Article of discussion: https://www.pnas.org/content/117/12/6630
In this episode, we discuss the effect of SARS CoV2 on dendritic cells and T cell responses through the article from Allo et al. Article of discussion: https://www.pnas.org/content/117/12/6630
What is the role of CD28 for activation of T cells? When is it dispensable? Is it required for anti-tumor immunity? Find out here! Article of discussion: https://pubmed.ncbi.nlm.nih.gov/28919076/
