Category: Blog

  • Neutrophils- the friend turned foe during heart attack

    Neutrophils- the friend turned foe during heart attack

    Just as we don’t care much about the guy running around with a bow and arrow in the Avengers (what was his name again?), platelets are also one of the most underappreciated characters of the human blood cell lore. Platelets are pivotal for orchestrating the process of sealing wounds from foreign invaders (clotting). However, excessive […]

  • Companions or parasites? A story of innate immunity and the hair mites.

    Companions or parasites? A story of innate immunity and the hair mites.

    Picture source: dreamstime.com When we injure our skin, it opens an attractive gate for external invaders, such as bacteria, to rush in. This activates our innate immunity, “the body’s first line of defense”, which therefore triggers the immune cells to stream in immediately to act as a barricade. As a next step, these immune cells release […]

  • I got it from my Mama: Maternal factors regulating a child’s neurodevelopmental disorders

    I got it from my Mama: Maternal factors regulating a child’s neurodevelopmental disorders

    Created with BioRender.com Just like humans, the life of most other animals is highly influenced by what the embryo experiences while in the mother’s womb, during birth, or by conditions following their birth. Neurodevelopmental, inflammatory, and metabolic defects in the offspring may stem from adverse conditions endured by the pregnant mother. These conditions might fare from […]

  • Sugar, yes please, won’t you come and put it down on macrophage: A song of sugars and cancers

    Sugar, yes please, won’t you come and put it down on macrophage: A song of sugars and cancers

    Our immune system is a well-orchestrated fort, equipped to fight all kinds of nasty that attack our body. Unfortunately, some attackers come well prepared with weapons for immune evasion and can escape or even confuse our immune system, such as with cancer. In the recent years, we have seen a rise of new potential therapies […]

  • Searching Salmonella infections for a cancer cure

    Searching Salmonella infections for a cancer cure

    Picture source: Science News The cure for cancer has been used as a talking point for decades. Even the current US president, Joe Biden, promised to cure cancer during his campaign. We certainly don’t need to convince anyone that studying anticancer therapies is an important research topic.  According to the CDC, in the United States […]

  • Are CAR Tregs a reason for CAR therapy failure?

    Are CAR Tregs a reason for CAR therapy failure?

    Created with Biorender.com On 12th of September 2022, Zinaida Good, a postdoctoral fellow at Stanford University, tweeted: “We found a CAR Treg subset in CD19-CAR T cells for lymphoma. We hope that this finding will put us on a path from 40% cure to 100% cure”.Only five years earlier, FDA had made historical approval for […]

  • Silica particles vs. the immune system

    Silica particles vs. the immune system

    Let’s cover a topic that is rarely discussed in immunology – Silicosis. Have you ever imagined what happens when you breathe in silica? Silica particles cause a severe condition called silicosis. As Ganesan et al. explain that silicosis is a fibrotic lung disease caused by the inhalation of respirable silica particles. Where can we be […]

  • The biomechanics of lymph node swelling

    The biomechanics of lymph node swelling

    At times when we fall sick, barely noticeable lumps can be felt under our skin. These lumps are our swollen lymph nodes, and they indicate the body’s immune system reacting to infectious agents. Historically, while we were trying to figure out the immune system and its fundamental cellular components, the complexity and dynamicity of lymph […]

  • Another Novel Zoonotic Virus: The Langya henipavirus!

    Another Novel Zoonotic Virus: The Langya henipavirus!

    Picture source: CDC Recent reports from the eastern region of China in the New England Journal of Medicine mentioned 35 patients showing feverish symptoms, infected with a novel zoonotic virus (virus of animal origin that can infect humans). The virus, Langya henipavirus (LayV), was named after the town “Langya“ where the first patient infected with […]

  • A Sheep in Wolf’s Clothing: Mimicking Tumor with Probiotic

    A Sheep in Wolf’s Clothing: Mimicking Tumor with Probiotic

    Created using BioRender.com Take a look in the mirror. What do you see? Given that you are reading an immunology blog, I hope your answer would be something along the line of a human being, or Homo sapiens if you want to be fancy. Now, let’s take a closer look together! At the genetic level, […]