Category: Blog

  • The biomechanics of lymph node swelling

    The biomechanics of lymph node swelling

    At times when we fall sick, barely noticeable lumps can be felt under our skin. These lumps are our swollen lymph nodes, and they indicate the body’s immune system reacting to infectious agents. Historically, while we were trying to figure out the immune system and its fundamental cellular components, the complexity and dynamicity of lymph […]

  • Another Novel Zoonotic Virus: The Langya henipavirus!

    Another Novel Zoonotic Virus: The Langya henipavirus!

    Picture source: CDC Recent reports from the eastern region of China in the New England Journal of Medicine mentioned 35 patients showing feverish symptoms, infected with a novel zoonotic virus (virus of animal origin that can infect humans). The virus, Langya henipavirus (LayV), was named after the town “Langya“ where the first patient infected with […]

  • A Sheep in Wolf’s Clothing: Mimicking Tumor with Probiotic

    A Sheep in Wolf’s Clothing: Mimicking Tumor with Probiotic

    Created using BioRender.com Take a look in the mirror. What do you see? Given that you are reading an immunology blog, I hope your answer would be something along the line of a human being, or Homo sapiens if you want to be fancy. Now, let’s take a closer look together! At the genetic level, […]

  • Novel role of immune cells in hair growth

    Novel role of immune cells in hair growth

    We normally lose from 50 to 100 hairs every day. Whether we notice it or not, lost hair is replaced with newly growing ones all the time. So far, we know of several factors that can disrupt this balance and lead to significant hair loss; including heredity, hormonal changes, infectious agents, medications (for instance drugs […]

  • The One where he Receives a Pig’s Heart

    The One where he Receives a Pig’s Heart

    Throughout history, people have experimented with transplantation and transfusion. Until the discovery of Human Leukocyte Antigen, blood groups, and tissue typing – donors commonly consisted of animals. My favorite one was using lamb blood because of religious aspects (Lamb of God), although it did not work as often. Expected, right? However, today with genetic modification […]

  • On the Cutting Edge: The OMICS Generation

    On the Cutting Edge: The OMICS Generation

    The last two decades have seen rapid development in almost every aspect of human life, and the field of biomedicine is no different. By the time the Human Genome Project concluded, the field of genomics had already observed a steady drop in the cost of sequencing. In years that followed, the technology developed rapidly, and […]

  • Unleashing the Anti-tumor Immune Cells with Dostarlimab

    Unleashing the Anti-tumor Immune Cells with Dostarlimab

    Blocking checkpoint proteins enhance immune cell activity In healthy individuals, the immune system is intricately regulated to maintain homeostasis. Consider it as a see-saw: on the one hand, excessive immune activation in the absence of harmful pathogens may manifest as autoimmune diseases; on the other hand, inadequate immune defense creates vulnerability during infections. The immune […]

  • Can our adipose tissue handle an infection?

    Can our adipose tissue handle an infection?

    A little fat won’t kill you – well, this may be a lie, but could I interest you in a story where a little fat could ‘save’ you after infection? This discovery definitely got my motor running. Could the adipocyte (a fat cell) act as an immune cell and clear the infection? Unfortunately, Caputa et […]

  • Shifting Paradigms: T Cells, FlipFlops, and Reversed T Cells

    Shifting Paradigms: T Cells, FlipFlops, and Reversed T Cells

    You must have come across the fundamental concepts of T cell development during your immunology class. Briefly, in the thymus, T cells expressing both CD4 and CD8 coreceptors interact with MHC molecules on thymic epithelial cells to make lineage fate decisions. CD4+ cells interact with MHCII and are called T helper cells while CD8+ cells […]