Can our adipose tissue handle an infection?
A little fat won’t kill you – well, this may be a lie, but could I interest you in a story where a little fatContinue reading “Can our adipose tissue handle an infection?”
Shifting Paradigms: T Cells, FlipFlops, and Reversed T Cells
You must have come across the fundamental concepts of T cell development during your immunology class. Briefly, in the thymus, T cells expressing both CD4Continue reading “Shifting Paradigms: T Cells, FlipFlops, and Reversed T Cells”
The Battle of the Ts: Regulatory CD8+ T cells suppress autoimmunity associated CD4+ T cells
“The enemy of my enemy is my friend” – Proverb Over years of evolution, our immune system successfully dealt with a variety of foreign invadersContinue reading “The Battle of the Ts: Regulatory CD8+ T cells suppress autoimmunity associated CD4+ T cells”
A Camel to the Rescue: Nanobodies against SARS-CoV-2
Created with BioRender.com Amid the COVID-19 pandemic, antibodies have been under the spotlight as potential therapeutics. Antibodies patrol the body and bind to their specific targetContinue reading “A Camel to the Rescue: Nanobodies against SARS-CoV-2”
Neutrophils help organs heal
Most of us had our knees bruised when we were kids: riding a bicycle, climbing the trees, playing soccer… and it was so fascinating toContinue reading “Neutrophils help organs heal”
A Way Through the Crowd: Motility of macrophages in a dense microenvironment
Macrophages – the most versatile and multipurpose cells of the immune system – scavenge away pathogens and sick cells to protect us from diseases. We have previouslyContinue reading “A Way Through the Crowd: Motility of macrophages in a dense microenvironment”
Toxoplasma gondii – a new cancer fighting superhero
“Life will win over death, and light will win over darkness”– Volodymyr Zelenskyy, President of Ukraine “I would not be here today if it wasn’tContinue reading “Toxoplasma gondii – a new cancer fighting superhero”
An Unexpected Linkage: The Gut-Skin Axis
Created with BioRender.com In the public discussion of microbes, there is often a negative connotation attached to microbes such as bacteria, viruses, fungi, and parasitesContinue reading “An Unexpected Linkage: The Gut-Skin Axis”
New Role for Ductal Cells in Type 1 Diabetes
Despite owning the same genetic material, our cells carry out highly specialized functions and vary from each other in many phenotypic aspects. Interestingly, when inContinue reading “New Role for Ductal Cells in Type 1 Diabetes”
Microbiota makes our intestines move and keeps the worms away
Image source: CDC The word “infection” is often associated with either bacteria or virus, but we all know there are some other bad guys thatContinue reading “Microbiota makes our intestines move and keeps the worms away”
Slowing Down Inflamm-Aging with Diet
Source: istock What if I tell you that you can greatly improve your immune system by just cutting your calories by 40%? If you areContinue reading “Slowing Down Inflamm-Aging with Diet”
A better method for T cell isolation is not so enigMATIC anymore
When we talk on the topic of cancer therapies, the first one that comes to my mind is adoptive T cell therapy using tumor-infiltrating lymphocytesContinue reading “A better method for T cell isolation is not so enigMATIC anymore”
A Song of Marrow and Microbes
Stem cells! Iron! Macrophages! Red blood cells! Butyrate! Gut microbiota! No, we are not just blurting out random terms (stick with us till the end toContinue reading “A Song of Marrow and Microbes”
Host microbiota affects the brain’s innate immune system
“I’m Gonna Make Him an Offer He Can’t Refuse.” -Don Vito Corleone It could be a quote from a dialogue between the host microbiota andContinue reading “Host microbiota affects the brain’s innate immune system”
A step towards affordable cell therapy using mRNA technology
This image was created with Biorender.com A decade ago, a novel immunotherapy ravaged two pounds of cancer cells and revolutionized the treatment of blood cancer.Continue reading “A step towards affordable cell therapy using mRNA technology”
The Immune side of Endometriosis
“One is not born, but rather becomes, a woman.” – Simone de Beauvoir. Throughout the years, young girls have been taught that with their firstContinue reading “The Immune side of Endometriosis”
The Spoils of Epstein-Barr Virus and Its Role in Multiple Sclerosis
Picture source: iStock, Health Central 2022 is off to a great start for Science as Harvard researchers published a study that potentially solves a longstandingContinue reading “The Spoils of Epstein-Barr Virus and Its Role in Multiple Sclerosis”
Welcome to Immunity, Red Blood Cells
In our childhood, we have been taught that our blood cells are divided into immune cells or white blood cells and non-immune cells containing redContinue reading “Welcome to Immunity, Red Blood Cells”
Goodnight, Sleep tight, don’t take your immunity light!
“Early to bed and early to rise makes one healthy, wealthy and wise.” Day and night have existed for as long as the earth andContinue reading “Goodnight, Sleep tight, don’t take your immunity light!”
OMV-based vaccines for SARS-CoV-2
Picture source: Dr. Matt Delisa, Locally Sourced Science The development, production, and manufacturing of large-scale vaccines are necessary for control of the pandemic internationally- toContinue reading “OMV-based vaccines for SARS-CoV-2“
Now take a deep breath and calm your immune system.
Throughout the COVID-19 outbreak we witnessed the good (rapid vaccine development and production, alongside the amazing work done by our healthcare workers), the bad (misinformationContinue reading “Now take a deep breath and calm your immune system.”
SARS-CoV2 Mu variant is resistant towards serum antibody neutralization
Picture source: 11Alive It is no news, vaccination against SARS-CoV-2 enormously decreases chances of severe side effects and hospitalizations, but vaccinated individuals are still notContinue reading “SARS-CoV2 Mu variant is resistant towards serum antibody neutralization”
The COVID-19 Research Rundown
The grim COVID-19 pandemic shows no sign of stopping, with the Delta variant bringing new waves of infections across the world. Thankfully, the vaccination effortsContinue reading “The COVID-19 Research Rundown”
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