Author: Lalitgr
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Our Innate Immune Proteins May Have Originated From Bacterial Anti-phage Proteins
Evolutionary biologists believe that advanced eukaryotic life evolved from less advanced life forms, and no I’m not talking about those hairy apes. Rather dial back the clock even further — way back to the point of genesis and we have our very first forefathers, the single-celled prokaryotic bacteria! Our eukaryotic cells share a huge deal…
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The Hunger games- The quest for survival of B cells in the germinal center
The journey of constantly going back and forth, from the dark side to the light side, is not one that’s reserved just for the strongest Jedis of the galaxy but one that’s also shared by the maturing B cells in our immune system. But unlike the former, it’s not the galaxy testing their fate, but…
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Dementia, a prologue to Alzheimer’s, and potential therapeutic targets
Imagine your brain as a library. Each book stacked on the shelves of this humongous, complex, intricately designed library is an individual memory. Strangely, all the books are pretty much within your reach, but then something sinister starts to happen. Slowly and gradually each book starts getting placed on the topmost shelf. You tiptoe and…
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Neutrophils- the friend turned foe during heart attack
Just as we don’t care much about the guy running around with a bow and arrow in the Avengers (what was his name again?), platelets are also one of the most underappreciated characters of the human blood cell lore. Platelets are pivotal for orchestrating the process of sealing wounds from foreign invaders (clotting). However, excessive…
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I got it from my Mama: Maternal factors regulating a child’s neurodevelopmental disorders
Created with BioRender.com Just like humans, the life of most other animals is highly influenced by what the embryo experiences while in the mother’s womb, during birth, or by conditions following their birth. Neurodevelopmental, inflammatory, and metabolic defects in the offspring may stem from adverse conditions endured by the pregnant mother. These conditions might fare from…